Medically Reviewed by Mahammad Juber, MD on March 06, 2025
Is There an Alternative to Lupus Medicine?
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Is There an Alternative to Lupus Medicine?

Many medicines reduce lupus inflammation and ease flares. Still, more than half of people with lupus try alternative therapies. While some people claim natural products improve their symptoms, little scientific evidence exists to prove these products work. In fact, some supplements can make lupus symptoms worse or interact with medicines you take. That’s why you need to check with your doctor before you try any new remedy.

Turmeric
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Turmeric

This yellow spice used in Indian cuisine is also a staple of traditional Asian medicine. Practitioners use it for skin, joint, and digestive diseases. Curcumin, the active ingredient in turmeric, has anti-inflammatory properties. In one small study, people with lupus who took turmeric supplements had lower blood pressure and fewer signs of kidney damage. This spice might also help protect bones against damage from corticosteroids. 

Ginger
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Ginger

Ginger, a spice made from the root of the same name, contains an anti-inflammatory compound called gingerol. In some studies, ginger reduced osteoarthritis pain and inflammation. Whether it might have the same effect in lupus is hard to say. Most of the evidence on ginger for lupus comes from studies of mice, not people. Until research reveals more, it's safe to add ginger to your food, but ask your doctor before you try supplements.

Omega-3s
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Omega-3s

These healthy fats found in fish, walnuts, and flaxseeds have anti-inflammatory properties that might make them useful for treating autoimmune diseases like lupus. In a few studies, people with lupus who took omega-3 supplements had less active disease. Omega-3s from supplements or food probably won't slow the disease enough on their own, but they might be a useful add-on to lupus medications.

Green Tea
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Green Tea

Tea has been an essential part of traditional Chinese medicine for centuries. It has caught on in the West for its healing potential, too. EGCG is the chemical in green tea that's behind many of its healthful properties. It's an antioxidant that helps protect cells from damage. In one small study, people with lupus who took green tea extract every day for 3 months had less active disease and better health overall.

Quercetin
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Quercetin

This chemical gives grapes, cherries, and berries their vibrant colors. It's also a powerful antioxidant and anti-inflammatory. But when it comes to lupus, what we know about quercetin comes mostly from lab and animal studies. Until we have more human studies, it's best to get this nutrient from fruits and vegetables. Quercetin supplements can cause headaches, upset stomach and, in large doses, kidney damage.

Vitamin D
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Vitamin D

Vitamin D is essential for strong bones and a healthy immune system, and people with lupus may run low on it. Your body makes D when the sun hits your skin. But the sun can trigger lupus symptoms in some people. Also, corticosteroids, a common lupus treatment, change the way your body uses vitamin D and can lead to deficiencies. A blood test can measure your vitamin D levels to see whether you might need a supplement. 

Olive Oil
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Olive Oil

Olive oil is a main source of fat in the Mediterranean diet. The secret to its healthfulness is plant chemicals called phenols. They reduce inflammation and help regulate the immune system. Because olive oil may also help protect against heart disease, type 2 diabetes, and cancer, it's a worthy addition to any healthy diet. Look for the extra-virgin kind. It's produced without high heat or chemicals, which preserves more of its nutrients.

Grapes 
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Grapes 

Resveratrol is an antioxidant in grape skins. Lab and animal studies show that it might protect against kidney failure and heart disease in people with lupus, but it doesn't seem to protect against other complications. You can get resveratrol from grapes and grape juice, as well as supplements. It's also in red wine, but alcohol may not mix well with your lupus medications. To be safe, check with your doctor before you drink.

MSM
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MSM

Methylsulfonylmethane (MSM) is a plant-based supplement often used for osteoarthritis pain, stiffness, and swelling. Whether it also relieves lupus pain is still unknown. Researchers haven’t done a study to confirm its effects. If you want to give it a shot anyway, check with your doctor first. MSM can cause nausea, diarrhea, and a stomachache in some people.